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1 records shown · first 60Genetic Polymorphisms of Vascular Endothelial Growth Factor and Their Impact on Recurrent Spontaneous Miscarriage in Saudi Women.
PMID 40429899 | PMCID PMC12112548 | DOI 10.3390/ijms26104757 · International journal of molecular sciences · 2025 · 8 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs10434 | “DNA was extracted from the buffy coat and analyzed for VEGF polymorphisms (rs10434, rs3025053, rs699947, rs2010963, rs833061, and rs25648) using TaqMan Real-Time PCR.” | 0.90 | hgvs_regex_v1 |
| phenotype | infertility | “Disruptions in vascular development, such as those due to variations in VEGF gene expression, may contribute to infertility and pregnancy complications.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “Genetic Polymorphisms of Vascular Endothelial Growth Factor and Their Impact on Recurrent Spontaneous Miscarriage in Saudi Women. This study investigated the impact of VEGF gene polymorphisms on RSM in Saudi women. Blood samples were collected from 200 Saudi women (100 cases with RSM and 100 controls). VEGF polymorphisms, along with reduced VEGF serum levels, are associated with an increased risk of RSM in Saudi women.” | 0.95 | saudi_context_rules_v1 |
| variant | rs3025053 | “DNA was extracted from the buffy coat and analyzed for VEGF polymorphisms (rs10434, rs3025053, rs699947, rs2010963, rs833061, and rs25648) using TaqMan Real-Time PCR.” | 0.90 | hgvs_regex_v1 |