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1 records shown · first 60Influence of adiposity-related genetic markers in a population of saudi arabians where other variables influencing obesity may be reduced.
PMID 25484485 | PMCID PMC4251424 | DOI 10.1155/2014/758232 · Disease markers · 2014 · 6 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs10767664 | “We observed large effect sizes with obesity for rs10767664 (BDNF) (OR = 1.923, P = 0.00072) and rs3751812 (FTO) (OR = 1.523, P = 0.016) in our sample and, using weighted genetic risk scores, we found strong evidence of a cumulative effect using 11 SNPs taken predominantly from loci principally affecting appetite (OR = 2.57, P = 0.00092).” | 0.90 | hgvs_regex_v1 |
| gene | BDNF | “We observed large effect sizes with obesity for rs10767664 (BDNF) (OR = 1.923, P = 0.00072) and rs3751812 (FTO) (OR = 1.523, P = 0.016) in our sample and, using weighted genetic risk scores, we found strong evidence of a cumulative effect using 11 SNPs taken predominantly from loci principally affecting appetite (OR = 2.57, P = 0.00092).” | 0.98 | hgnc_dict_v1 |
| gene | FTO | “We observed large effect sizes with obesity for rs10767664 (BDNF) (OR = 1.923, P = 0.00072) and rs3751812 (FTO) (OR = 1.523, P = 0.016) in our sample and, using weighted genetic risk scores, we found strong evidence of a cumulative effect using 11 SNPs taken predominantly from loci principally affecting appetite (OR = 2.57, P = 0.00092).” | 0.98 | hgnc_dict_v1 |
| phenotype | obesity | “Influence of adiposity-related genetic markers in a population of saudi arabians where other variables influencing obesity may be reduced.” | 0.98 | phenotype_alias_lexicon_v2 |