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1 records shown · first 60Study of gene polymorphisms in Toll-like receptor 2 in patients with acute lymphoblastic leukemia.
PMID 39040297 | PMCID PMC11261853 | DOI 10.1016/j.heliyon.2024.e33754 · Heliyon · 2024 · 8 validated mentions
Evidence preview
| Type | Entity | Source evidence | Confidence | Extractor |
|---|---|---|---|---|
| variant | rs1339 | “In total, Five SNPs were statistically evaluated in the TLR2 (rs1898830 A/G, rs3804099 T/C, rs3804100 T/C, rs1339 T/C, and rs1337 C/G), which may influence the susceptibility of ALL.” | 0.90 | hgvs_regex_v1 |
| gene | TLR2 | “Toll-like receptor 2 (TLR2) play an essential role in innate immunity.” | 0.98 | hgnc_dict_v1 |
| phenotype | leukemia | “Study of gene polymorphisms in Toll-like receptor 2 in patients with acute lymphoblastic leukemia.” | 0.98 | phenotype_alias_lexicon_v2 |
| population | Saudi Arabia | “Study of gene polymorphisms in Toll-like receptor 2 in patients with acute lymphoblastic leukemia. CONCLUSIONS: This study shows that TLR2 could be an independent prognostic factor of ALL risks in the Saudi population.” | 0.95 | saudi_context_rules_v1 |