asthma
SaudiVarKB evidence summary derived from retained literature mentions.
212Phenotype mentions
100Publications
50Associated gene records
50Associated variant records
Associated gene records
Co-mentioned in the same publications| Gene | Identifier / context | Articles | Mentions |
|---|---|---|---|
| TLR4 | HGNC:11850 | 3 | 3 |
| SIRT1 | HGNC:14929 | 2 | 2 |
| FOXP3 | HGNC:6106 | 2 | 2 |
| CD4 | HGNC:1678 | 2 | 2 |
| STAT6 | HGNC:11368 | 2 | 2 |
| HDAC2 | HGNC:4853 | 2 | 2 |
| G6PD | HGNC:4057 | 2 | 2 |
| DOCK8 | HGNC:19191 | 2 | 2 |
| STAT3 | HGNC:11364 | 2 | 2 |
| LDLR | HGNC:6547 | 2 | 2 |
| S100A9 | HGNC:10499 | 2 | 2 |
| TSLP | HGNC:30743 | 2 | 2 |
| FLG | HGNC:3748 | 2 | 2 |
| SOD2 | HGNC:11180 | 2 | 2 |
| TYROBP | HGNC:12449 | 2 | 2 |
| TLR2 | HGNC:11848 | 2 | 2 |
| CD14 | HGNC:1628 | 2 | 2 |
| S100A8 | HGNC:10498 | 2 | 2 |
| ITGB2 | HGNC:6155 | 2 | 2 |
| CCR3 | HGNC:1604 | 2 | 2 |
| MUC5AC | HGNC:7515 | 2 | 2 |
| PARP1 | HGNC:270 | 1 | 1 |
| COL1A1 | HGNC:2197 | 1 | 1 |
| TNF | HGNC:11892 | 1 | 1 |
| MC2R | HGNC:6930 | 1 | 1 |
| MRAP | HGNC:1304 | 1 | 1 |
| NLRP3 | HGNC:16400 | 1 | 1 |
| CD34 | HGNC:1662 | 1 | 1 |
| CD40 | HGNC:11919 | 1 | 1 |
| HBB | HGNC:4827 | 1 | 1 |
| MAGT1 | HGNC:28880 | 1 | 1 |
| CARD11 | HGNC:16393 | 1 | 1 |
| ADA | HGNC:186 | 1 | 1 |
| PEPD | HGNC:8840 | 1 | 1 |
| MPO | HGNC:7218 | 1 | 1 |
| PTEN | HGNC:9588 | 1 | 1 |
| IL17RA | HGNC:5985 | 1 | 1 |
| TET2 | HGNC:25941 | 1 | 1 |
| TGM1 | HGNC:11777 | 1 | 1 |
| NPNT | HGNC:27405 | 1 | 1 |
| CDC42 | HGNC:1736 | 1 | 1 |
| CARMIL2 | HGNC:27089 | 1 | 1 |
| DOCK2 | HGNC:2988 | 1 | 1 |
| LRRK2 | HGNC:18618 | 1 | 1 |
| AGL | HGNC:321 | 1 | 1 |
| ABCB1 | HGNC:40 | 1 | 1 |
| BRAF | HGNC:1097 | 1 | 1 |
| AKT1 | HGNC:391 | 1 | 1 |
| IMPACT | HGNC:20387 | 1 | 1 |
| GLS | HGNC:4331 | 1 | 1 |
Associated variant records
Co-mentioned in the same publications| Variant | Identifier / context | Articles | Mentions |
|---|---|---|---|
| p.Arg347His | p.Arg347His | 1 | 1 |
| c.580dup | c.580dup | 1 | 1 |
| rs7975232 | rs7975232 | 1 | 1 |
| rs1544410 | rs1544410 | 1 | 1 |
| rs731236 | rs731236 | 1 | 1 |
| rs10192157 | rs10192157 | 1 | 1 |
| 1646C>T | 1646C>T | 1 | 1 |
| rs2899642 | rs2899642 | 1 | 1 |
| 27C>G | 27C>G | 1 | 1 |
| 1625G>A | 1625G>A | 1 | 1 |
| 1534C>G | 1534C>G | 1 | 1 |
| p.W577C | p.W577C | 1 | 1 |
| G894T | G894T | 1 | 1 |
| p.Y59D | p.Y59D | 1 | 1 |
| rs17880588 | rs17880588 | 1 | 1 |
| rs17878530 | rs17878530 | 1 | 1 |
| rs763780 | rs763780 | 1 | 1 |
| rs11465553 | rs11465553 | 1 | 1 |
| rs2397084 | rs2397084 | 1 | 1 |
| rs2228570 | rs2228570 | 1 | 1 |
| rs5743708 | rs5743708 | 1 | 1 |
| rs187084 | rs187084 | 1 | 1 |
| rs11096956 | rs11096956 | 1 | 1 |
| rs1800925 | rs1800925 | 1 | 1 |
| c.-93+487C>T | c.-93+487C>T | 1 | 1 |
| rs20541 | rs20541 | 1 | 1 |
| p.Gln144Arg | p.Gln144Arg | 1 | 1 |
| rs3804099 | rs3804099 | 1 | 1 |
| rs3804100 | rs3804100 | 1 | 1 |
| rs4819554 | rs4819554 | 1 | 1 |
| rs879577 | rs879577 | 1 | 1 |
| rs41323645 | rs41323645 | 1 | 1 |
| rs4819555 | rs4819555 | 1 | 1 |
| rs4880 | rs4880 | 1 | 1 |
| p.Val16Ala | p.Val16Ala | 1 | 1 |
| rs4986790 | rs4986790 | 1 | 1 |
| rs4986791 | rs4986791 | 1 | 1 |
| p.Arg107Ter | p.Arg107Ter | 1 | 1 |
| c.319C>T | c.319C>T | 1 | 1 |
| rs61816764 | rs61816764 | 1 | 1 |
| rs9303277 | rs9303277 | 1 | 1 |
| rs2763979 | rs2763979 | 1 | 1 |
| rs3816470 | rs3816470 | 1 | 1 |
| rs7216389 | rs7216389 | 1 | 1 |
| rs8067378 | rs8067378 | 1 | 1 |
| rs12603332 | rs12603332 | 1 | 1 |
| rs1837253 | rs1837253 | 1 | 1 |
| rs2738047 | rs2738047 | 1 | 1 |
| rs1047031 | rs1047031 | 1 | 1 |
| rs1799946 | rs1799946 | 1 | 1 |
Associated population records
Co-mentioned in the same publicationsSupporting publications
100 records- 2026Campesterol attenuates airway inflammation in allergic asthma: insights from a murine model and molecular docking analysis.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Anti-inflammatory and anti-allergic potential of liquiritin extracted from Glycyrrhiza glabra L. in asthma management.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Targeting gasdermin D-mediated pyroptosis: a precision anti-inflammatory strategy for acute and chronic lung diseases.Inflammopharmacology1 mentions
- 2026Unraveling the metabolic potential of Moringa oleifera derived metabolites in combating Parkinson's and Alzheimer's disease.Bioorganic chemistry1 mentions
- 2026The Genetic Factors Controlling the Accumulation of Amylase/Trypsin Inhibitors (ATIs) in Barley for Enhancing Human Nutrition and Health.Food science & nutrition1 mentions
- 2026Comparative analysis of the morphological heterogeneity of smooth muscle cells in two avian species: the muscovy Duck (Cairina moschata) and the Japanese quail (Coturnix japonica): ultrastructural and histochemical study.Protoplasma1 mentions
- 2026Phosphodiesterase signaling in asthma: mechanistic insights and emerging therapeutic strategies.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2026Predictors of Fatal Anaphylaxis: A Systematic Review.International archives of allergy and immunology1 mentions
- 2026Temporal trends and determinants of ED visits in sickle cell disease: a multicenter EHR study from Saudi Arabia (2016-2021).Frontiers in medicine1 mentions
- 2026Physical inactivity in chronic airways disease: an important candidate in the treatable traits paradigm.European respiratory review : an official journal of the European Respiratory Society1 mentions
- 2026Case Report: Novel MAGT1 pathogenic variant with significant atopy, hypogammaglobulinemia and viral skin infections.Frontiers in immunology1 mentions
- 2026Biological implications and therapeutic potential of phosphodiesterase inhibitors: A review.Medicine1 mentions
- 2026Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study.American journal of clinical dermatology1 mentions
- 2026Interleukin-35 as a key immunoregulatory mediator in steroid-hyporesponsive severe asthma.Frontiers in immunology1 mentions
- 2026Characteristics of Patients with Severe Uncontrolled Asthma in Saudi Arabia: A Cross-Sectional Study.Journal of asthma and allergy1 mentions
- 2026Comparative efficacy and safety of biologic therapies in pediatric asthma: a comprehensive systematic review.Frontiers in medicine1 mentions
- 2026A Novel Homozygous Truncating CD8A Variant (p.Arg107Ter) in a Patient with Recurrent Sinopulmonary Infections: A Case Report and Literature Review.Healthcare (Basel, Switzerland)1 mentions
- 2026Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies.Food science & nutrition1 mentions
- 2026Prevalence and factors associated with self-reported asthma diagnosis in Makkah Region of Saudi Arabia.Medicine1 mentions
- 2026Functional and Resistome Profiling of Paediatric Airway Microbiota in Asthma Using Shotgun Metagenomics.Biomedicines1 mentions
- 2026X-Linked immune dysregulation, polyendocrinopathy, and enteropathy (IPEX) syndrome with concurrent membranous and IgA nephropathy: a case report.BMC nephrology1 mentions
- 2026Tezepelumab: redefining TSLP blockade in severe asthma through mechanistic precision and translational pharmacology.Frontiers in pharmacology1 mentions
- 2026Hospital-Based Proportion of Diabetic Retinopathy and Associated Risk Factors Among Patients With Type 2 Diabetes Mellitus.Cureus1 mentions
- 2026Acute exacerbation of chronic rhinosinusitis: clinical and microbiological perspectives from a Saudi tertiary care center.Annals of Saudi medicine1 mentions
- 2026Exploring the potential efficacy of Ziziphus spina-christi on restoring steroid sensitivity in severe asthma.Fitoterapia1 mentions
- 2025Potential Impact of SOD2 (rs4880; p.Val16Ala) Variant with the Susceptibility for Childhood Bronchial Asthma.Biochemical genetics1 mentions
- 2025Inhibiting DNA Sensing Pathway Controls Steroid Hyporesponsive Lung Inflammation.Advanced biology1 mentions
- 2025Ethnobotany, bioactive compounds and pharmacology of Syzygium guineense (Willd.) DC: A review.Journal of ethnopharmacology1 mentions
- 2025IL13 gene polymorphisms among Sudanese patients with bronchial asthma: a case-control study.Molecular biology research communications1 mentions
- 2025Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies.Food science & nutrition1 mentions
- 2025Clinical Epidemiology and Phenotypic Characteristics of Hidradenitis Suppurativa Disease in the Central Region of Saudi Arabia: Findings from a Cross-Sectional.Clinical, cosmetic and investigational dermatology1 mentions
- 2025The Use of PediSTAT Application by Paramedics Working in Saudi Arabia to Reduce the Risk of Medication Error for Pediatric Patients.Pediatric reports1 mentions
- 2025Regional challenges to optimize the management of patients with severe asthma type 2 inflammation: a Delphi consensus in seven countries.The Journal of asthma : official journal of the Association for the Care of Asthma1 mentions
- 2025Examining the Prevalence, Characteristics, and Potential Links Between Skin Disorders and Autism Spectrum Disorder (ASD).Journal of clinical medicine1 mentions
- 2025Unraveling the role of lncRNA in Endometriosis-Associated immune system Dysregulation: Exploring the intricate immunological changes and disrupted signaling pathways.Human immunology1 mentions
- 2025Intranasal dupilumab improves responsiveness to steroid in an asthma mouse model.Inflammation research : official journal of the European Histamine Research Society ... [et al.]1 mentions
- 2025Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology1 mentions
- 2025Physiological Small Airways Dysfunction and the Bronchodilator Response in Adults With Asthma and Its Risk Factors: A Retrospective Analysis.Journal of asthma and allergy1 mentions
- 2025Exogenous sex steroid hormones and asthma phenotypes: a study protocol for a prospective cohort analysis with UK-wide primary care data.BMJ open1 mentions
- 2025Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity.Immunity, inflammation and disease1 mentions
- 2025Risk Factors of Post-Craniotomy Surgical Site Infection: A Retrospective Study.Surgical infections1 mentions
- 2025Role of Toll-like Receptors Nine and Ten Polymorphisms in Childhood Bronchial Asthma Control and Their Relation to Cardiac Function.Diagnostics (Basel, Switzerland)1 mentions
- 2025Prevalence of Allergic Rhinitis Among Children and Its Characteristics in Al-Qassim Region, Saudi Arabia.Cureus1 mentions
- 2025Exploring the Long-Term Utility of Remotely Monitored FeNO Suppression Testing in Severe Asthma.The journal of allergy and clinical immunology. In practice1 mentions
- 2025Defining Clinical Remission in Severe Asthma: Expert Opinion From the Gulf Region Using the Modified Delphi Method.Respiratory medicine1 mentions
- 2025Calprotectin inhibition attenuates silica-induced lung fibrosis.Inflammopharmacology1 mentions
- 2025Prevalence of Asthma Symptoms and Environmental Triggers Among School-Aged Children in the Eastern Province of Saudi Arabia.Cureus1 mentions
- 2025Prevalence of Respiratory Symptoms in Individuals With Down's Syndrome in Saudi Arabia: A Cross-Sectional Study.Journal of applied research in intellectual disabilities : JARID1 mentions
- 2025Prevalence and Risk Factors of Asthma Among Iraq Adults: A Cross-Sectional Study.Journal of asthma and allergy1 mentions
- 2025Inflammatory lung diseases: a clinical and scientific review of the latest advances and challenges.Pharmacological reports : PR1 mentions
- 2025Biomarker profile and disease burden associated with intermittent and long-term oral corticosteroid use in patients with severe asthma prior to biologic initiation in real-life (STAR).The World Allergy Organization journal1 mentions
- 2025Dysregulation and gene polymorphisms of Vitamin D receptor: its implications in lipid metabolic disorders.Molecular biology reports1 mentions
- 2025Assessment of Public Awareness and Prevalence of Asthma Comorbidities in Al-Qunfudhah, Saudi Arabia.Cureus1 mentions
- 2025Plant-based traditional remedies and their role in public health: ethnomedicinal perspectives for a growing population.Journal of health, population, and nutrition1 mentions
- 2025Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.Frontiers in pharmacology1 mentions
- 2025Clinical and molecular findings in actin-related inborn errors of immunity: the middle East and North Africa registry.Frontiers in genetics1 mentions
- 2025Response to Biologics Along a Gradient of T2 Involvement in Patients With Severe Asthma: A Data-Driven Biomarker Clustering Approach.The journal of allergy and clinical immunology. In practice1 mentions
- 2025Cissus quadrangularis Revealed as a Potential Source of Anti-Inflammatory and Anti-Diabetic Pharmacophore in Experimental and Computational Studies.Chemistry & biodiversity1 mentions
- 2025Anesthetic implications of elective cesarean section in a parturient with Noonan syndrome and complex cardiomyopathy: A case report.Saudi journal of anaesthesia1 mentions
- 2025Association of TLR2 (rs5743708) Gene Polymorphism with Asthma Susceptibility and the Impact of Smoking: (Case-Control Study).La Clinica terapeutica1 mentions
- 2025A review on clinical implications of S100 proteins in lung diseases.Frontiers in medicine1 mentions
- 2025Estragole protects against ovalbumin-induced allergic asthma by amelioration of interleukin-4 and interleukin-5 expression in BALB/c mice.Journal of molecular histology1 mentions
- 2025Prognostic factors for survival and recurrence in papillary thyroid carcinoma: a retrospective study.Gland surgery1 mentions
- 2025Efficacy and Safety of Dupilumab in Children With Moderate-to-Severe Asthma: A Systematic Review of Emerging Phase 3 Evidence.Pediatric pulmonology1 mentions
- 2025Thrombotic complications in critically ill patients with coronavirus infections: A comparative study of MERS and COVID-19.Medicine1 mentions
- 2025Dupilumab for atopic manifestations in pediatric patients with inborn errors of immunity: efficacy and safety in a genetically diverse cohort.Frontiers in immunology1 mentions
- 2025Asthma-related school absenteeism: Prevalence, disparities, and the need for comprehensive management: A systematic review and meta-analysis.Dialogues in health1 mentions
- 2024Allergic Airway Inflammation Emerges from Gut Inflammation and Leakage in Mouse Model of Asthma.Advanced biology1 mentions
- 2024Investigating the T regulatory cells and Sirtuin-I serum level in immunotherapy treated house dust mite allergic asthma patients.The Journal of asthma : official journal of the Association for the Care of Asthma1 mentions
- 2024Unwinding circular RNA's role in inflammatory pulmonary diseases.Naunyn-Schmiedeberg's archives of pharmacology1 mentions
- 2024Risk factors for acute chest syndrome among children with sickle cell anemia hospitalized for vaso-occlusive crises.Scientific reports1 mentions
- 2024Cystic Lung Changes, Bronchiectasis, and a Heterozygous-Primary Ciliary Dyskinesia-Associated Variant in the DNAH5 Gene: A Diagnostic Challenge.The American journal of case reports1 mentions
- 2024Evolving Epidemiology of Pediatric Respiratory Syncytial Virus (RSV) Cases Around COVID-19 Pandemic: Impact and Clinical Insights, Retrospective Cohort Study.Journal of epidemiology and global health1 mentions
- 2024Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan.Frontiers in veterinary science1 mentions
- 2024Integrating Network Pharmacology and Molecular Docking Approach to Elucidate the Mechanism of Commiphora wightii for the Treatment of Rheumatoid Arthritis.Bioinformatics and biology insights1 mentions
- 2024Recent advances in the therapeutic applications of selenium nanoparticles.Molecular biology reports1 mentions
- 2024Association of TLR4 gene rs4986790 and rs4986791 polymorphisms with asthma susceptibility: meta-analysis and trial sequential analysis.Annals of Saudi medicine1 mentions
- 2024Awareness of Side Effects of Corticosteroids among Users and Nonusers in Saudi Arabia.Journal of pharmacy & bioallied sciences1 mentions
- 2024Impact of Interleukin-17 Receptor A Gene Variants on Asthma Susceptibility and Clinical Manifestations in Children and Adolescents.Children (Basel, Switzerland)1 mentions
- 2024Acute Motor Conduction Block Neuropathy After Initiation of Omalizumab: Case Report and Literature Review for Possible Causality.eNeurologicalSci1 mentions
- 2024Frequency of Severe Asthma and Its Clinical Phenotypes at the Asthma Clinic in One of the Largest Sudanese Tertiary Pediatric Hospitals: A Cross-Sectional Hospital-Outpatient-Based Study.Journal of asthma and allergy1 mentions
- 2024IL-35 promotes IL-35+IL-10+ Bregs and Conventional LAG3+ Tregs in the lung tissue of OVA-Induced Asthmatic Mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.]1 mentions
- 2024Assessment of Knowledge and Practices of Medical Emergencies in Medical and Dental Students of the University of Ha'il, Saudi Arabia: A Cross-Sectional Study.Cureus1 mentions
- 2024Cachexia in tuberculosis in South-East Asian and African regions: knowledge gaps and untapped opportunities.Annals of medicine and surgery (2012)1 mentions
- 2024Exploring food-specific IgG responses in pediatric allergic disorders: A retrospective cross-sectional study.Allergologia et immunopathologia1 mentions
- 2024lncRNA-mediated immune system dysregulation in RIF; a comprehensive insight into immunological modifications and signaling pathways' dysregulation.Human immunology1 mentions
- 2024Interleukin-33 mediated regulation of microRNAs in human cord blood-derived mast cells: Implications for infection, immunity, and inflammation.PloS one1 mentions
- 2024Network Pharmacology and Molecular Docking Reveal Anti-Asthmatic Potential of Zephyranthes rosea Lindl. in an Ovalbumin-Induced Asthma Model.Pharmaceuticals (Basel, Switzerland)1 mentions
- 2024Designing a multi-epitope vaccine candidate against human rhinovirus C utilizing immunoinformatics approach.Frontiers in immunology1 mentions
- 2024Asthma and Atopic Diseases in Children with Autism Spectrum Disorders.Journal of pharmacy & bioallied sciences1 mentions
- 2023Association between 17q21 variants and asthma predisposition in Pashtun population from Pakistan.The Journal of asthma : official journal of the Association for the Care of Asthma1 mentions
- 2023Early recognition of pulmonary complications of sickle cell disease.Saudi medical journal1 mentions
- 2023Morbidity profile among older people at primary health care centers in Saudi Arabia during the period 2012-2020.Saudi medical journal1 mentions
- 2023Bronchial Asthma Exacerbation in the Emergency Department in a Saudi Pediatric Population: An Insight From a Tertiary Hospital in Riyadh, Saudi Arabia.Cureus1 mentions
- 2023Evaluation of Antidiabetic, Antioxidant and Anti-Hyperlipidemic Effects of Solanum indicum Fruit Extract in Streptozotocin-Induced Diabetic Rats.Current issues in molecular biology1 mentions
- 2023Bruton's tyrosine kinase inhibition suppresses neutrophilic inflammation and restores histone deacetylase 2 expression in myeloid and structural cells in a mixed granulocytic mouse model of asthma.International immunopharmacology1 mentions
- 2023Comparative effectiveness of anti-IL5 and anti-IgE biologic classes in patients with severe asthma eligible for both.Allergy1 mentions
- 2023Modeling the Effects of Cypermethrin Toxicity on Ovalbumin-Induced Allergic Pneumonitis Rats: Macrophage Phenotype Differentiation and p38/STAT6 Signaling Are Candidate Targets of Pirfenidone Treatment.Cells1 mentions
- 2023Prevalence and Risk Factors of Allergic Diseases Among School Students in Tabuk: A Cross-Sectional Study.Cureus1 mentions
- 2023Inhibition of non-receptor tyrosine kinase LCK partially mitigates mixed granulocytic airway inflammation in a murine model of asthma.International immunopharmacology1 mentions